Pu Lab Publications 2014

  • Lin, Z., von Gise, A., Zhou, P., Gu, F., Ma, Q., Jiang, J., Yau, A. L., Buck, J. N., Gouin, K. A., van Gorp, P. R., Zhou, B., Chen, J., Seidman, J. G., Wang, D. Z. & Pu, W. T. Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine Myocardial Infarction Model. Circ Res (2014). PDF
  • Wang, G., McCain, M. L., Yang, L., He, A., Pasqualini, F. S., Agarwal, A., Yuan, H., Jiang, D., Zhang, D., Zangi, L., Geva, J., Roberts, A. E., Ma, Q., Ding, J., Chen, J., Wang, D. Z., Li, K., Wang, J., Wanders, R. J., Kulik, W., Vaz, F. M., Laflamme, M. A., Murry, C. E., Chien, K. R., Kelley, R. I., Church, G. M., Parker, K. K. & Pu, W. T. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nat Med (2014). PDF SI Movies Podcast
  • Prendiville, T. W., Ma, Q., Lin, Z., Zhou, P., He, A. & Pu, W. T. Ultrasound-guided Transthoracic Intramyocardial Injection in Mice. J Vis Exp (2014). PDF Video
  • Li, K., Wang, G., Andersen, T., Zhou, P. & Pu, W. T. Optimization of Genome Engineering Approaches with the CRISPR/Cas9 System. PLoS One 9, e105779 (2014). PDF
  • Lin, Z., Zhou, P., von Gise, A., Gu, F., Ma, Q., Chen, J., Guo, H., van Gorp, P. R., Wang, D. Z. & Pu, W. T. Pi3kcb Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote Cardiomyocyte Proliferation and Survival. Circ Res (2014). PDF
  • He, A., Gu, F., Hu, Y., Ma, Q., Yi Ye, L., Akiyama, J. A., Visel, A., Pennacchio, L. A. & Pu, W. T. Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. Nat Commun 5, 4907 (2014). PDF
  • Yang, L., Grishin, D., Wang, G., Aach, J., Zhang, C. Z., Chari, R., Homsy, J., Cai, X., Zhao, Y., Fan, J. B., Seidman, C., Seidman, J., Pu, W. T. & Church, G. Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells. Nat Commun 5, 5507 (2014). PDF

2014 Reviews/Editorials
  • Prendiville, T., Jay, P.Y., and Pu, W.T. (2014). Insights into the Genetic Structure of Congenital Heart Disease from Human and Murine Studies on Monogenic Disorders. Cold Spring Harb Perspect Med 4. PDF
  • Zhang, B., and Pu, W.T. (2014). Notching up vascular regeneration. Cell Res. PDF
  • Lin, Z. & Pu, W. T. Strategies for cardiac regeneration and repair. Science Translational Medicine. PDF
  • Lin, Z. & Pu, W. T. Harnessing Hippo in the heart: Hippo/YAP1 signaling and applications to heart regeneration and rejuvenation. Stem Cell Research. PDF.
  • Hu, Y. & Pu, W. T. Hippo activation in arrhythmogenic cardiomyopathy. Circ Res 114, 402-405 (2014). PDF

Collaborative Work
  • Aronson, B.E., Rabello Aronson, S., Berkhout, R.P., Chavoushi, S.F., He, A., Pu, W.T., Verzi, M.P., and Krasinski, S.D. (2014). GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27. Biochim Biophys Acta
  • Sartori, D. J., Wilbur, C. J., Long, S. Y., Rankin, M. M., Li, C., Bradfield, J. P., Hakonarson, H., Grant, S. F., Pu, W. T. & Kushner, J. A. GATA Factors Promote ER Integrity and β-Cell Survival and Contribute to Type 1 Diabetes Risk. Mol Endocrinol 28, 28-39 (2014).
  • Zhang, H., von Gise, A., Liu, Q., Hu, T., Tian, X., He, L., Pu, W., Huang, X., He, L., Cai, C. L., Camargo, F. D., Pu, W. T. & Zhou, B. Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion. J Biol Chem (2014).
  • Tian, X., Hu, T., Zhang, H., He, L., Huang, X., Liu, Q., Yu, W., He, L., Yang, Z., Yan, Y., Yang, X., Zhong, T. P., Pu, W. T. & Zhou, B. De novo formation of a distinct coronary vascular population in neonatal heart. Science 345, 90-94 (2014).