Pu Lab Publications 2019


Original Research

  • Wang, S., Chen, J., Garcia, S. P., Liang, X., Zhang, F., Yan, P., Yu, H., Wei, W., Li, Z., Wang, J., Le, H., Han, Z., Luo, X., Day, D. S., Stevens, S. M., Zhang, Y., Park, P. J., Liu, Z.-J., Sun, K., Yuan, G.-C., Pu, W. T.* & Zhang, B. A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA. Genome Res. 29, 193–207 (2019). *co-corresponding. Cover article. PDF.
  • Bezzerides, V. J., Caballero, A., Wang, S., Ai, Y., Hylind, R. J., Lu, F., Heims-Waldron, D. A., Chambers, K. D., Zhang, D., Abrams, D. J. & Pu, W. T. Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia by Inhibition of Ca2+/Calmodulin-Dependent Kinase II. Circulation (2019). doi:10.1161/CIRCULATIONAHA.118.038514. Circulation. PDF. SI. Commentary in Nat. Rev. Cardiol.
  • Park S-J, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu, F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK. Insights into the pathogenesis of catecholaminergic polymorphic ventricular tachycardia from engineered human heart tissue. Circulation. PDF.
  • Akerberg*, B. N., Gu*, F., VanDusen, N. J., Zhang, X., Dong, R., Li, K., Zhang, B., Zhou, B., Sethi, I., Ma, Q., Wasson, L., Wen, T., Liu, J., Dong, K., Conlon, F. L., Zhou, J., Yuan, G.-C., Zhou, P. & Pu, W. T. A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers. Nat. Commun. 10, 4907 (2019). PDF.

2019 Reviews/Editorials

  • Austin, K. M., Trembley, M. A., Chandler, S. F., Sanders, S. P., Saffitz, J. E., Abrams, D. J. & Pu, W. T. Molecular mechanisms of arrhythmogenic cardiomyopathy. Nat. Rev. Cardiol. (2019). doi:10.1038/s41569-019-0200-7. PDF.
  • Akerberg, B. N. & Pu, W. T. Genetic and Epigenetic Control of Heart Development. Cold Spring Harb. Perspect. Biol. (2019). doi:10.1101/cshperspect.a036756. PDF.

Collaborative Work

  • MacQueen, L. A., Sheehy, S. P., Chantre, C. O., Zimmerman, J. F., Pasqualini, F. S., Liu, X., Goss, J. A., Campbell, P. H., Gonzalez, G. M., Park, S.-J., Capulli, A. K., Ferrier, J. P., Kosar, T. F., Mahadevan, L., Pu, W. T. & Parker, K. K. A tissue-engineered scale model of the heart ventricle. Nat Biomed Eng 2, 930–941 (2018). Cover article.
  • Gao, F., Kataoka, M., Liu, N., Liang, T., Huang, Z.-P., Gu, F., Ding, J., Liu, J., Zhang, F., Ma, Q., Wang, Y., Zhang, M., Hu, X., Kyselovic, J., Hu, X., Pu, W. T., Wang, J. ’an, Chen, J. & Wang, D.-Z. Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction. Nat. Commun. 10, 1802 (2019).
  • Berry, J. L., Zhu, W., Tang, Y. L., Krishnamurthy, P., Ge, Y., Cooke, J. P., Chen, Y., Garry, D. J., Yang, H.-T., Rajasekaran, N. S., Koch, W. J., Li, S., Domae, K., Qin, G., Cheng, K., Kamp, T. J., Ye, L., Hu, S., Ogle, B. M., Rogers, J. M., Abel, E. D., Davis, M. E., Prabhu, S. D., Liao, R., Pu, W. T., Wang, Y., Ping, P., Bursac, N., Vunjak-Novakovic, G., Wu, J. C., Bolli, R., Menasché, P. & Zhang, J. Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circ. Res. 124, 161–169 (2019).
  • Pierpont, M. E., Brueckner, M., Chung, W. K., Garg, V., Lacro, R. V., McGuire, A. L., Mital, S., Priest, J. R., Pu, W. T., Roberts, A., Ware, S. M., Gelb, B. D., Russell, M. W. & American Heart Association Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; and Council on Genomic and Precision Medicine. Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association. Circulation 138, e653–e711 (2018).