Pu Lab Publications 2024


2024 Original Manuscripts


  • Lu, F., Liou, C., Ma, Q., Wu, Z., Xue, B., Xia, Y., Xia, S., Trembley, M. A., Ponek, A., Xie, W., Shani, K., Bortolin, R. H., Prondzynski, M., Berkson, P., Zhang, X., Naya, F. J., Bedi, K. C., Margulies, K. B., Zhang, D., Parker, K. K. & Pu, W. T. Virally delivered CMYA5 enhances the assembly of cardiac dyads. Nat. Biomed. Eng. (2024). Full Text.
  • Bortolin, R. H., Nawar, F., Park, C., Trembley, M. A., Prondzynski, M., Sweat, M. E., Wang, P., Chen, J., Lu, F., Liou, C., Berkson, P., Keating, E. M., Yoshinaga, D., Pavlaki, N., Samenuk, T., Cavazzoni, C. B., Sage, P. T., Ma, Q., Whitehill, R. D., Abrams, D. J., Carreon, C. K., Putra, J., Alexandrescu, S., Guo, S., Tsai, W.-C., Rubart, M., Kubli, D., Mullick, A. E., Bezzerides, V. J. & Pu, W. T. Antisense oligonucleotide therapy for calmodulinopathy. Circulation (2024). Full Text.
  • Guo, C.-T., Jardin, B. D., Lin, J.-S., Ambroise, R. L., Wang, Z., Yang, L.-Z., Mazumdar, N., Lu, F.-J., Ma, Q., Cao, Y.-P., Liu, C.-Z., Li, K.-L., Liu, X.-J., Lan, F., Zhao, M.-M., Xiao, H., Dong, E.-D., Pu, W. T. & Guo, Y.-X. In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-disc-associated mitigator of isoproterenol-induced cardiac injury. Acta Pharmacol. Sin. (2024). PDF.
  • Prondzynski, M., Berkson, P., Trembley, M. A., Tharani, Y., Shani, K., Bortolin, R. H., Sweat, M. E., Mayourian, J., Yucel, D., Cordoves, A. M., Gabbin, B., Hou, C., Anyanwu, N. J., Nawar, F., Cotton, J., Milosh, J., Walker, D., Zhang, Y., Lu, F., Liu, X., Parker, K. K., Bezzerides, V. J. & Pu, W. T. Efficient and reproducible generation of human iPSC-derived cardiomyocytes and cardiac organoids in stirred suspension systems. Nat. Commun. 15, 5929 (2024). Full Text.
  • Xiao, F., Zhang, X., Morton, S. U., Kim, S. W., Fan, Y., Gorham, J. M., Zhang, H., Berkson, P. J., Mazumdar, N., Cao, Y., Chen, J., Hagen, J., Liu, X., Zhou, P., Richter, F., Shen, Y., Ward, T., Gelb, B. D., Seidman, J. G., Seidman, C. E. & Pu, W. T. Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease. Nat. Genet. 56, 420–430 (2024). PDF.
  • Chen, J., Zhang, X., DeLaughter, D. M., Trembley, M. A., Saifee, S., Xiao, F., Chen, J., Zhou, P., Seidman, C. E., Seidman, J. G. & Pu, W. T. Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution. Circ. Res. 134, 529–546 (2024). PDF.

2024 Reviews/Editorials/Book Chapters

  • Bezzerides, V. J. & Pu, W. T. in Nadas’ Pediatric Cardiology 790–802 (Elsevier, 2025).
  • Yucel, D. & Pu, W. T. From vitality to vulnerability: the impact of oxygen on cardiac function and regeneration. J. Cardiovasc. Aging 4, (2024).

2024 Collaborative Work

  • Broman, M. T., Nadadur, R. D., Perez-Cervantes, C., Burnicka-Turek, O., Lazarevic, S., Gams, A., Laforest, B., Steimle, J. D., Iddir, S., Wang, Z., Smith, L., Mazurek, S. R., Olivey, H. E., Zhou, P., Gadek, M., Shen, K. M., Khan, Z., Theisen, J. W. M., Yang, X. H., Ikegami, K., Efimov, I. R., Pu, W. T., Weber, C. R., McNally, E. M., Svensson, E. C. & Moskowitz, I. P. A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation (2024). doi:10.1161/CIRCULATIONAHA.123.066804
  • He, X., Yang, T., Lu, Y. W., Wu, G., Dai, G., Ma, Q., Zhang, M., Zhou, H., Long, T., Yan, Y., Liang, Z., Liu, C., Pu, W. T., Dong, Y., Ou, J., Chen, H., Mably, J. D., He, J., Wang, D.-Z. & Huang, Z.-P. The long noncoding RNA CARDINAL attenuates cardiac hypertrophy by modulating protein translation. J. Clin. Invest. 134, (2024).
  • Wang, Y., Zhang, M., Wang, R., Lin, J., Ma, Q., Guo, H., Huang, H., Liang, Z., Cao, Y., Zhang, X., Lu, Y. W., Liu, J., Xiao, F., Yan, H., Dimitrova, N., Huang, Z.-P., Mably, J. D., Pu, W. T. & Wang, D.-Z. Therapeutic Inhibition of LincRNA-p21 Protects Against Cardiac Hypertrophy. Circ. Res. (2024). doi:10.1161/CIRCRESAHA.123.323356
  • Yang, L., Liu, Z., Chen, G., Chen, Z., Guo, C., Ji, X., Cui, Q., Sun, Y., Hu, X., Zheng, Y., Li, Y., Gao, F., Chen, L., Zhou, P., Pu, W. T. & Guo, Y. MicroRNA-122-Mediated Liver Detargeting Enhances the Tissue Specificity of Cardiac Genome Editing. Circulation 149, 1778–1781 (2024).