Pu Lab Publications 2021


2021 Original Manuscripts

  • Liu X, Wang S, Guo X, Li Y, Ogurlu R, Lu F, Prondzynski M, de la Serna Buzon S, Ma Q, Zhang D, Wang G, Cotton J, Guo Y, Xiao L, Milan DJ, Xu Y, Schlame M, Bezzerides VJ, Pu WT. Increased ROS-Mediated CaMKII Activation Contributes to Calcium Handling Abnormalities and Impaired Contraction in Barth Syndrome. Circulation. 2021 Apr 1; Available from: http://dx.doi.org/10.1161/CIRCULATIONAHA.120.048698. PDF.
  • Guo Y, Cao Y, Jardin BD, Sethi I, Ma Q, Moghadaszadeh B, Troiano EC, Mazumdar N, Trembley MA, Small EM, Yuan G-C, Beggs AH, Pu WT. Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling. Proc Natl Acad Sci U S A [Internet]. 2021 Jan 12;118(2). Available from: http://dx.doi.org/10.1073/pnas.2008861118. PDF.
  • Wang S, Guo Y, Pu WT. AAV Gene Transfer to the Heart. Methods Mol Biol. 2021;2158:269–80. PDF.
  • VanDusen, N. J., Lee, J. Y., Gu, W., Butler, C. E., Sethi, I., Zheng, Y., King, J. S., Zhou, P., Suo, S., Guo, Y., Ma, Q., Yuan, G.-C. & Pu, W. T. Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation. Nat. Commun. 12, 4442 (2021). Link.

2021 Reviews/Editorials

  • Wang S, Pu WT. Calcific aortic valve disease: turning therapeutic discovery up a notch. Nat Rev Cardiol [Internet]. 2021 Feb 19; Available from: http://dx.doi.org/10.1038/s41569-021-00528-1. PDF.
  • Bezzerides VJ, Pu WT. Two sides of the same coin: new insights into mechanisms of ventricular fibrillation. Cardiovasc Res. 2021 Mar 21;117(4):983–4.

2021 Collaborative Work

  • Yu H, Zhang F, Yan P, Zhang S, Lou Y, Geng Z, Li Z, Zhang Y, Xu Y, Lu Y, Chen C, Wang D, Zhu W, Hu X, Wang J ’an, Zhuang T, Zhang Y, Wu G, Liu J, Zeng C, Pu WT, Sun K, Zhang B. LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation [Internet]. 2021 Mar 5;0(0). Available from: http://dx.doi.org/10.1161/CIRCULATIONAHA.120.050812
  • Liu J, Wen T, Dong K, He X, Zhou H, Shen J, Fu Z, Hu G, Ma W, Li J, Wang W, Wang L, Akerberg BN, Xu J, Osman I, Zheng Z, Wang W, Du Q, Pu WT, Xiang M, Chen W, Su H, Zhang W, Zhou J. TEAD1 protects against necroptosis in postmitotic cardiomyocytes through regulation of nuclear DNA-encoded mitochondrial genes. Cell Death Differ [Internet]. 2021 Jan 19; Available from: http://dx.doi.org/10.1038/s41418-020-00732-5
  • Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, Bernard LD, Akerberg BN, Gu F, Li K, Speir ML, Haeussler M, Pu WT, Stuart JM, Seidman CE, Seidman JG, Heyn H, Bruneau BG. Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. Dev Cell. 2021 Feb 8;56(3):292–309.e9.
  • Dalal, J. S., Winden, K. D., Salussolia, C. L., Sundberg, M., Singh, A., Pham, T. T., Zhou, P., Pu, W. T., Miller, M. T. & Sahin, M. Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts. Elife 10, (2021).
  • Gao, Y., Sun, Y., Ercan-Sencicek, A. G., King, J. S., Akerberg, B. N., Ma, Q., Kontaridis, M. I., Pu, W. T. & Lin, Z. YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. Int. J. Mol. Sci. 22, (2021).